Liposomes and lipid nanoparticles
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Publications:
 | Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery Erica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui, Junbiao Wang, Augusto Amici, Cristina Marchini, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, August 2021 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | A Proteomic Study on the Personalized Protein Corona of Liposomes. Relevance for Early Diagnosis of Pancreatic DUCTAL Adenocarcinoma and Biomarker Detection Luca Digiacomo, Francesca Giulimondi, Daniela Pozzi, Alessandro Coppola, Vincenzo La Vaccara, Damiano Caputo, Giulio Caracciolo Published in Journal of Nanotheranostics, June 2021 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
 | Optimal centrifugal isolating of liposome–protein complexes from human plasma Luca Digiacomo, Francesca Giulimondi, Anna Laura Capriotti, Susy Piovesana, Carmela Maria Montone, Riccardo Zenezini Chiozzi, Aldo Laganà, Morteza Mahmoudi, Daniela Pozzi, Giulio Caracciolo Published in Nanoscale Advances, March 2021 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
 | A comprehensive analysis of liposomal biomolecular corona upon human plasma incubation: The evolution towards the lipid corona Giorgia La Barbera, Anna Laura Capriotti, Giulio Caracciolo, Chiara Cavaliere, Andrea Cerrato, Carmela Maria Montone, Susy Piovesana, Daniela Pozzi, Erica Quagliarini, Aldo Laganà Published in Talanta, March 2020 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
 | A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression Sara Palchetti, Luca Digiacomo, Francesca Giulimondi, Daniela Pozzi, Giovanna Peruzzi, Gianmarco Ferri, Heinz Amenitsch, Francesco Cardarelli, Morteza Mahmoudi, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Impact of the protein corona on nanomaterial immune response and targeting ability Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Alessandra Zingoni, Giulio Caracciolo Published in Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, January 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles, Graphene Oxide and hybrid nanomaterials Type: Review |
 | Interplay of protein corona and immune cells controls blood residency of liposomes Francesca Giulimondi, Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Elisabetta Vulpis, Anna Laura Capriotti, Riccardo Zenezini Chiozzi, Aldo Laganà, Heinz Amenitsch, Laura Masuelli, Giovanna Peruzzi, Morteza Mahmoudi, Isabella Screpanti, Alessandra Zingoni, Giulio Caracciolo Published in Nature communications, August 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Disease-specific protein corona sensor arrays may have disease detection capacity Giulio Caracciolo, Reihaneh Safavi-Sohi, Reza Malekzadeh, Hossein Poustchi, Mahdi Vasighi, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Aldo Laganà, Mohammad Hajipour, Marina Di Domenico, Angelina Di Carlo, Damiano Caputo, Haniyeh Aghaverdi, Massimiliano Papi, Valentina Palmieri, Angela Santoni, Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Kenneth S Suslick, Morteza Mahmoudi Published in Nanoscale Horizons, June 2019 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
| | Effect of molecular crowding on the biological identity of liposomes: an overlooked factor at the bio-nano interface Luca Digiacomo, Francesca Giulimondi, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale Advances, May 2019 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
 | Exploitation of nanoparticle-protein interactions for early disease detection Massimiliano Papi, Valentina Palmieri, Sara Palchetti, Daniela Pozzi, Luca Digiacomo, Elia Guadagno, Marialaura del Basso De Caro, Marina Di Domenico, Serena Ricci, Roberto Pani, Morteza Mahmoudi, Angelina Di Carlo, Giulio Caracciolo Published in Applied Physics Letters, April 2019 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
| | Protein corona fingerprints of liposomes: New opportunities for targeted drug delivery and early detection in pancreatic cancer Sara Palchetti, Damiano Caputo, Luca Digiacomo, Anna Laura Capriotti, Roberto Coppola, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, January 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
 | Cationic lipid/DNA complexes manufactured by microfluidics and bulk self-assembly exhibit different transfection behavior Luca Digiacomo, Sara Palchetti, Daniela Pozzi, Augusto Amici, Giulio Caracciolo, Cristina Marchini Published in Biochemical and biophysical research communications, September 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Improving the accuracy of pancreatic cancer clinical staging by exploitation of nanoparticle-blood interactions: a pilot study Damiano Caputo, Maria Cristina Cartillone, Chiara Cascone, Daniela Pozzi, Luca Digiacomo, Sara Palchetti, Giulio Caracciolo, Roberto Coppola Published in Pancreatology, September 2018 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
 | Brain targeting by liposome–biomolecular corona boosts anticancer efficacy of temozolomide in glioblastoma cells Antonietta Arcella, Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Anna Laura Capriotti, Luigi Frati, Maria Antonietta Oliva, Georgia Tsaouli, Rossella Rota, Isabella Screpanti, Morteza Mahmoudi, Giulio Caracciolo Published in ACS Chemical Neuroscience, July 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Human biomolecular corona of liposomal doxorubicin: The overlooked factor in anticancer drug delivery Giulio Caracciolo, Sara Palchetti, Luca Digiacomo, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Heinz Amenitsch, Paolo Maria Tentori, Valentina Palmieri, Massimiliano Papi, Francesco Cardarelli, Daniela Pozzi, Aldo Laganà Published in ACS applied materials & interfaces, June 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Clinically approved liposomal nanomedicines: lessons learned from the biomolecular corona Giulio Caracciolo Published in Nanoscale, January 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
| | An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles Luca Digiacomo, Francesco Cardarelli, Daniela Pozzi, Sara Palchetti, Michelle A. Digman, Enrico Gratton, Anna Laura Capriotti, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale, October 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Clinically approved PEGylated nanoparticles are covered by a protein corona that boosts the uptake by cancer cells Massimiliano Papi, Damiano Caputo, Valentina Palmieri, Roberto Coppola, Sara Palchetti, Francesca Bugli, Cecilia Martini, Luca Digiacomo, Daniela Pozzi, Giulio Caracciolo Published in Nanoscale, June 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Impact of the biomolecular corona on the structure of PEGylated liposomes Luca Digiacomo, Daniela Pozzi, Heinz Amenitsch, Giulio Caracciolo Published in Biomaterials science, June 2017 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
 | Influence of dynamic flow environment on nanoparticle-protein corona: From protein patterns to uptake in cancer cells Sara Palchetti, Daniela Pozzi, Anna Laura Capriotti, Giorgia La Barbera, Riccardo Zenezini Chiozzi, Luca Digiacomo, Giovanna Peruzzi, Giulio Caracciolo, Aldo Laganà Published in Colloids and Surfaces B: Biointerfaces, May 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Biological identity of nanoparticles in vivo: clinical implications of the protein corona Giulio Caracciolo, Omid C. Farokhzad, Morteza Mahmoudi Published in Trends in Biotechnology, March 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
 | Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells Sara Palchetti, Daniela Pozzi, Cristina Marchini, Augusto Amici, Cristina Andreani, Caterina Bartolacci, Luca Digiacomo, Valentina Gambini, Francesco Cardarelli, Carmine Di Rienzo, Giovanna Peruzzi, Heinz Amenitsch, Rocco Palermo, Isabella Screpanti, Giulio Caracciolo Published in Nanomedicine: Nanotechnology, Biology and Medicine, February 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | In vivo protein corona patterns of lipid nanoparticles Augusto Amici, Giulio Caracciolo, Luca Digiacomo, Valentina Gambini, Cristina Marchini, Martina Tilio, Anna Laura Capriotti, Valentina Colapicchioni, Roberto Matassa, Giuseppe Familiari, Sara Palchetti, Daniela Pozzi, Morteza Mahmoudi, Aldo Laganà Published in RSC advances, January 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | A protein corona-enabled blood test for early cancer detection Damiano Caputo, Massimiliano Papi, Roberto Coppola, Sara Palchetti, Luca Digiacomo, Giulio Caracciolo, Daniela Pozzi Published in Nanoscale, January 2017 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
 | Development of an image Mean Square Displacement (iMSD)-based method as a novel approach to study the intracellular trafficking of nanoparticles Luca Digiacomo, Michelle A. Digman, Enrico Gratton, Giulio Caracciolo Published in Acta biomaterialia, September 2016 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Nanoparticles-cell association predicted by protein corona fingerprints Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Giovanna Peruzzi, Elisa Micarelli, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale, June 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
 | Personalized liposome–protein corona in the blood of breast, gastric and pancreatic cancer patients Valentina Colapicchioni, Martina Tilio, Luca Digiacomo, Valentina Gambini, Sara Palchetti, Cristina Marchini, Daniela Pozzi, Sergio Occhipinti, Augusto Amici, Giulio Caracciolo Published in The international journal of biochemistry & cell biology, June 2016 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
 | The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery Francesco Cardarelli, Luca Digiacomo, Cristina Marchini, Augusto Amici, Fabrizio Salomone, Giuseppe Fiume, Alessandro Rossetta, Enrico Gratton, Daniela Pozzi, Giulio Caracciolo Published in Scientific reports, May 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
 | Exploring cellular interactions of liposomes using protein corona fingerprints and physicochemical properties Arafeh Bigdeli, Sara Palchetti, Daniela Pozzi, Mohammad Reza Hormozi-Nezhad, Francesca Baldelli Bombelli, Giulio Caracciolo, Morteza Mahmoudi Published in ACS nano, March 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
| | The protein corona of circulating PEGylated liposomes Sara Palchetti, Valentina Colapicchioni, Luca Digiacomo, Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Giorgia La Barbera, Aldo Laganà Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2016 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Stealth effect of biomolecular corona on nanoparticle uptake by immune cells Giulio Caracciolo, Sara Palchetti, Valentina Colapicchioni, Luca Digiacomo, Daniela Pozzi, Anna Laura Capriotti, Giorgia La Barbera, Aldo Laganà Published in Langmuir, October 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | The biomolecular corona of nanoparticles in circulating biological media Daniela Pozzi, Giulio Caracciolo, Luca Digiacomo, Valentina Colapicchioni, Sara Palchetti, Anna Laura Capriotti, Chiara Cavaliere, Riccardo Zenezini Chiozzi, Antonio Puglisi, Alado Laganà Published in Nanoscale, July 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Lipid composition: a ‘key factor’ for the rational manipulation of the liposome–protein corona by liposome design Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Heinz Amenitsch, Aldo Laganà Published in RSC advances, July 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
 | Surface chemistry and serum type both determine the nanoparticle–protein corona Daniela Pozzi, Giulio Caracciolo, Anna Laura Capriotti, Chiara Cavaliere, Giorgia La Barbera, Thomas J. Anchordoquy, Aldo Laganà Published in Journal of proteomics, April 2015 (see publication) Research themes: Liposomes and lipid nanoparticles Type: paper |
| | Liposome–protein corona in a physiological environment: challenges and opportunities for targeted delivery of nanomedicines Giulio Caracciolo Published in Nanomedicine: Nanotechnology, Biology and Medicine, April 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
| | Size and charge of nanoparticles following incubation with human plasma of healthy and pancreatic cancer patients Giulio Caracciolo, Damiano Caputo, Daniela Pozzi, Valentina Colapicchioni, Roberto Coppola Published in Colloids and Surfaces B: Biointerfaces, November 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: paper |
 | The liposome–protein corona in mice and humans and its implications for in vivo delivery Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Giorgia La Barbera, Augusto Amici, Alado Laganà Published in Journal of Materials Chemistry B, September 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Effect of polyethyleneglycol (PEG) chain length on the bio-nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells Daniela Pozzi, Valentina Colapicchioni, Giulio Caracciolo, Susy Piovesana, Anna Laura Capriotti, Sara Palchetti, Stefania De Grossi, Anna Riccioli, Heinz Amenitsch, Aldo Laganà Published in Nanoscale, March 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: interplay between nanostructure and composition Daniela Pozzi, Cristina Marchini, Francesco Cardarelli, Fabrizio Salomone, Stefano Coppola, Maura Montani, Maria Elexpuru Zabaleta, Michelle A. Digman, Enrico Gratton, Valentina Colapicchioni, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Selective targeting capability acquired with a protein corona adsorbed on the surface of 1, 2-dioleoyl-3-trimethylammonium propane/DNA nanoparticles Giulio Caracciolo, Francesco Cardarelli, Daniela Pozzi, Fabrizio Salomone, Giuseppe Maccari, Giuseppe Bardi, Anna Laura Capriotti, Chiara Cavaliere, Massimiliano Papi, Aldo Laganà Published in ACS applied materials & interfaces, December 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
 | Mechanistic understanding of gene delivery mediated by highly efficient multicomponent envelope-type nanoparticle systems Daniela Pozzi, Cristina Marchini, Francesco Cardarelli, Alessandro Rossetta, Valentina Colapicchioni, Augusto Amici, Maura Montani, Stefania Motta, Paola Brocca, Laura Cantù, Giulio Caracciolo Published in Molecular pharmaceutics, December 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Time evolution of nanoparticle–protein corona in human plasma: relevance for targeted drug delivery Ana Lilia Barrán-Berdón, Daniela Pozzi, Giulio Caracciolo, Anna Laura Capriotti, Giuseppe Caruso, Chiara Cavaliere, Anna Riccioli, Sara Palchetti, Aldo Laganà Published in Langmuir, April 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Cationic liposome/DNA complexes: from structure to interactions with cellular membranes Giulio Caracciolo, Heinz Amenitsch Published in European biophysics journal, October 2012 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
| | Cholesterol-dependent macropinocytosis and endosomal escape control the transfection efficiency of lipoplexes in CHO living cells Francesco Cardarelli, Daniela Pozzi, Angelo Bifone, Cristina Marchini, Giulio Caracciolo Published in Molecular pharmaceutics, February 2012 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Evolution of the protein corona of lipid gene vectors as a function of plasma concentration Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Patrizia Foglia, Heinz Amenitsch, Aldo Lagana Published in Langmuir, December 2011 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Surface adsorption of protein corona controls the cell internalization mechanism of DC-Chol–DOPE/DNA lipoplexes in serum Giulio Caracciolo, Luciano Callipo, Sofia Candeloro De Sanctis, Chiara Cavaliere, Daniela Pozzi, Aldo Laganà Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2010 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |