Heinz Amenitsch

Physicist by training Heinz is a multitalented scientist who introduced us to the amazing world of synchrotron SAXS more than 15 years ago. With his transversal knowledge and skills as well as his enthusiastic attitude, Heinz has been one of the main protagonists of the lab's growth. Going for experiments to the synchrotron SAXS beamline he leads in Trieste is always a pleasure for the lab’s staff and spending afterwards an unforgettable night with Heinz and his amazing wife Shiva is one of the most beautiful events of the year.

Some publications with our group

Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery Erica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui, Junbiao Wang, Augusto Amici, Cristina Marchini, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, August 2021 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression Sara Palchetti, Luca Digiacomo, Francesca Giulimondi, Daniela Pozzi, Giovanna Peruzzi, Gianmarco Ferri, Heinz Amenitsch, Francesco Cardarelli, Morteza Mahmoudi, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Interplay of protein corona and immune cells controls blood residency of liposomes Francesca Giulimondi, Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Elisabetta Vulpis, Anna Laura Capriotti, Riccardo Zenezini Chiozzi, Aldo Laganà, Heinz Amenitsch, Laura Masuelli, Giovanna Peruzzi, Morteza Mahmoudi, Isabella Screpanti, Alessandra Zingoni, Giulio Caracciolo Published in Nature communications, August 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Human biomolecular corona of liposomal doxorubicin: The overlooked factor in anticancer drug delivery Giulio Caracciolo, Sara Palchetti, Luca Digiacomo, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Heinz Amenitsch, Paolo Maria Tentori, Valentina Palmieri, Massimiliano Papi, Francesco Cardarelli, Daniela Pozzi, Aldo Laganà Published in ACS applied materials & interfaces, June 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Impact of the biomolecular corona on the structure of PEGylated liposomes Luca Digiacomo, Daniela Pozzi, Heinz Amenitsch, Giulio Caracciolo Published in Biomaterials science, June 2017 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper

Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells Sara Palchetti, Daniela Pozzi, Cristina Marchini, Augusto Amici, Cristina Andreani, Caterina Bartolacci, Luca Digiacomo, Valentina Gambini, Francesco Cardarelli, Carmine Di Rienzo, Giovanna Peruzzi, Heinz Amenitsch, Rocco Palermo, Isabella Screpanti, Giulio Caracciolo Published in Nanomedicine: Nanotechnology, Biology and Medicine, February 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Lipid composition: a ‘key factor’ for the rational manipulation of the liposome–protein corona by liposome design Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Heinz Amenitsch, Aldo Laganà Published in RSC advances, July 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper

Effect of polyethyleneglycol (PEG) chain length on the bio-nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells Daniela Pozzi, Valentina Colapicchioni, Giulio Caracciolo, Susy Piovesana, Anna Laura Capriotti, Sara Palchetti, Stefania De Grossi, Anna Riccioli, Heinz Amenitsch, Aldo Laganà Published in Nanoscale, March 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Cationic liposome/DNA complexes: from structure to interactions with cellular membranes Giulio Caracciolo, Heinz Amenitsch Published in European biophysics journal, October 2012 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review

Evolution of the protein corona of lipid gene vectors as a function of plasma concentration Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Patrizia Foglia, Heinz Amenitsch, Aldo Lagana Published in Langmuir, December 2011 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper