Augusto Amici and Cristina Marchini

Augusto and Cristina are biologists by training and introduced us to cell biology more than 15 years ago. The possibility of expanding the research of the lab in the biomedical field is mainly due to the passion and competence of Augusto and Cristina. The evenings spent together in the Camerino farmhouses with excellent food and wine have made our friendship stronger and inspired our research in the field of gene delivery.

Some publications with our group

Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery Erica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui, Junbiao Wang, Augusto Amici, Cristina Marchini, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, August 2021 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Cationic lipid/DNA complexes manufactured by microfluidics and bulk self-assembly exhibit different transfection behavior Luca Digiacomo, Sara Palchetti, Daniela Pozzi, Augusto Amici, Giulio Caracciolo, Cristina Marchini Published in Biochemical and biophysical research communications, September 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells Sara Palchetti, Daniela Pozzi, Cristina Marchini, Augusto Amici, Cristina Andreani, Caterina Bartolacci, Luca Digiacomo, Valentina Gambini, Francesco Cardarelli, Carmine Di Rienzo, Giovanna Peruzzi, Heinz Amenitsch, Rocco Palermo, Isabella Screpanti, Giulio Caracciolo Published in Nanomedicine: Nanotechnology, Biology and Medicine, February 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

In vivo protein corona patterns of lipid nanoparticles Augusto Amici, Giulio Caracciolo, Luca Digiacomo, Valentina Gambini, Cristina Marchini, Martina Tilio, Anna Laura Capriotti, Valentina Colapicchioni, Roberto Matassa, Giuseppe Familiari, Sara Palchetti, Daniela Pozzi, Morteza Mahmoudi, Aldo Laganà Published in RSC advances, January 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Personalized liposome–protein corona in the blood of breast, gastric and pancreatic cancer patients Valentina Colapicchioni, Martina Tilio, Luca Digiacomo, Valentina Gambini, Sara Palchetti, Cristina Marchini, Daniela Pozzi, Sergio Occhipinti, Augusto Amici, Giulio Caracciolo Published in The international journal of biochemistry & cell biology, June 2016 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper

The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery Francesco Cardarelli, Luca Digiacomo, Cristina Marchini, Augusto Amici, Fabrizio Salomone, Giuseppe Fiume, Alessandro Rossetta, Enrico Gratton, Daniela Pozzi, Giulio Caracciolo Published in Scientific reports, May 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper

The liposome–protein corona in mice and humans and its implications for in vivo delivery Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Giorgia La Barbera, Augusto Amici, Alado Laganà Published in Journal of Materials Chemistry B, September 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper

Mechanistic understanding of gene delivery mediated by highly efficient multicomponent envelope-type nanoparticle systems Daniela Pozzi, Cristina Marchini, Francesco Cardarelli, Alessandro Rossetta, Valentina Colapicchioni, Augusto Amici, Maura Montani, Stefania Motta, Paola Brocca, Laura Cantù, Giulio Caracciolo Published in Molecular pharmaceutics, December 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper