Nanocarriers for drug and gene delivery
text
Publications:
 | Microfluidic Formulation of DNA-Loaded Multicomponent Lipid Nanoparticles for Gene Delivery Erica Quagliarini, Serena Renzi, Luca Digiacomo, Francesca Giulimondi, Barbara Sartori, Heinz Amenitsch, Valentina Tassinari, Laura Masuelli, Roberto Bei, Lishan Cui, Junbiao Wang, Augusto Amici, Cristina Marchini, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, August 2021 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Mechanistic Insights into the Release of Doxorubicin from Graphene Oxide in Cancer Cells Erica Quagliarini, Riccardo Di Santo, Daniela Pozzi, Paolo Tentori, Francesco Cardarelli, Giulio Caracciolo Published in Nanomaterials, August 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Graphene Oxide and hybrid nanomaterials Type: Paper |
 | A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression Sara Palchetti, Luca Digiacomo, Francesca Giulimondi, Daniela Pozzi, Giovanna Peruzzi, Gianmarco Ferri, Heinz Amenitsch, Francesco Cardarelli, Morteza Mahmoudi, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Effect of Protein Corona on The Transfection Efficiency of Lipid-Coated Graphene Oxide-Based Cell Transfection Reagents Erica Quagliarini, Riccardo Di Santo, Sara Palchetti, Gianmarco Ferri, Francesco Cardarelli, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, February 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Graphene Oxide and hybrid nanomaterials Type: Paper |
 | Impact of the protein corona on nanomaterial immune response and targeting ability Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Alessandra Zingoni, Giulio Caracciolo Published in Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, January 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles, Graphene Oxide and hybrid nanomaterials Type: Review |
 | Interplay of protein corona and immune cells controls blood residency of liposomes Francesca Giulimondi, Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Elisabetta Vulpis, Anna Laura Capriotti, Riccardo Zenezini Chiozzi, Aldo Laganà, Heinz Amenitsch, Laura Masuelli, Giovanna Peruzzi, Morteza Mahmoudi, Isabella Screpanti, Alessandra Zingoni, Giulio Caracciolo Published in Nature communications, August 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | The biomolecular corona of gold nanoparticles in a controlled microfluidic environment Luca Digiacomo, Sara Palchetti, Francesca Giulimondi, Daniela Pozzi, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Aldo Laganà, Giulio Caracciolo Published in Lab on a Chip, June 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Nanomaterials for cancer detection Type: Paper |
 | Microfluidic-generated lipid-graphene oxide nanoparticles for gene delivery Riccardo Di Santo, Erica Quagliarini, Sara Palchetti, Daniela Pozzi, Valentina Palmieri, Giordano Perini, Massimiliano Papi, Anna Laura Capriotti, Aldo Laganà, Giulio Caracciolo Published in Applied Physics Letters, June 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Graphene Oxide and hybrid nanomaterials Type: Paper |
| | Protein corona fingerprints of liposomes: New opportunities for targeted drug delivery and early detection in pancreatic cancer Sara Palchetti, Damiano Caputo, Luca Digiacomo, Anna Laura Capriotti, Roberto Coppola, Daniela Pozzi, Giulio Caracciolo Published in Pharmaceutics, January 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper |
 | Microfluidic manufacturing of surface-functionalized graphene oxide nanoflakes for gene delivery Riccardo Di Santo, Luca Digiacomo, Sara Palchetti, Valentina Palmieri, Giordano Perini, Daniela Pozzi, Massimiliano Papi, Giulio Caracciolo Published in Nanoscale, January 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Graphene Oxide and hybrid nanomaterials Type: Paper |
 | Cationic lipid/DNA complexes manufactured by microfluidics and bulk self-assembly exhibit different transfection behavior Luca Digiacomo, Sara Palchetti, Daniela Pozzi, Augusto Amici, Giulio Caracciolo, Cristina Marchini Published in Biochemical and biophysical research communications, September 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Brain targeting by liposome–biomolecular corona boosts anticancer efficacy of temozolomide in glioblastoma cells Antonietta Arcella, Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Anna Laura Capriotti, Luigi Frati, Maria Antonietta Oliva, Georgia Tsaouli, Rossella Rota, Isabella Screpanti, Morteza Mahmoudi, Giulio Caracciolo Published in ACS Chemical Neuroscience, July 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Human biomolecular corona of liposomal doxorubicin: The overlooked factor in anticancer drug delivery Giulio Caracciolo, Sara Palchetti, Luca Digiacomo, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Heinz Amenitsch, Paolo Maria Tentori, Valentina Palmieri, Massimiliano Papi, Francesco Cardarelli, Daniela Pozzi, Aldo Laganà Published in ACS applied materials & interfaces, June 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Clinically approved liposomal nanomedicines: lessons learned from the biomolecular corona Giulio Caracciolo Published in Nanoscale, January 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
 | Dynamic fingerprinting of sub-cellular nanostructures by image mean square displacement analysis Luca Digiacomo, Francesca D’autilia, William Durso, Paolo Maria Tentori, Giulio Caracciolo, Francesco Cardarelli Published in Scientific reports, November 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery Type: Paper |
| | An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles Luca Digiacomo, Francesco Cardarelli, Daniela Pozzi, Sara Palchetti, Michelle A. Digman, Enrico Gratton, Anna Laura Capriotti, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale, October 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Clinically approved PEGylated nanoparticles are covered by a protein corona that boosts the uptake by cancer cells Massimiliano Papi, Damiano Caputo, Valentina Palmieri, Roberto Coppola, Sara Palchetti, Francesca Bugli, Cecilia Martini, Luca Digiacomo, Daniela Pozzi, Giulio Caracciolo Published in Nanoscale, June 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Influence of dynamic flow environment on nanoparticle-protein corona: From protein patterns to uptake in cancer cells Sara Palchetti, Daniela Pozzi, Anna Laura Capriotti, Giorgia La Barbera, Riccardo Zenezini Chiozzi, Luca Digiacomo, Giovanna Peruzzi, Giulio Caracciolo, Aldo Laganà Published in Colloids and Surfaces B: Biointerfaces, May 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Biological identity of nanoparticles in vivo: clinical implications of the protein corona Giulio Caracciolo, Omid C. Farokhzad, Morteza Mahmoudi Published in Trends in Biotechnology, March 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
 | Manipulation of lipoplex concentration at the cell surface boosts transfection efficiency in hard-to-transfect cells Sara Palchetti, Daniela Pozzi, Cristina Marchini, Augusto Amici, Cristina Andreani, Caterina Bartolacci, Luca Digiacomo, Valentina Gambini, Francesco Cardarelli, Carmine Di Rienzo, Giovanna Peruzzi, Heinz Amenitsch, Rocco Palermo, Isabella Screpanti, Giulio Caracciolo Published in Nanomedicine: Nanotechnology, Biology and Medicine, February 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | In vivo protein corona patterns of lipid nanoparticles Augusto Amici, Giulio Caracciolo, Luca Digiacomo, Valentina Gambini, Cristina Marchini, Martina Tilio, Anna Laura Capriotti, Valentina Colapicchioni, Roberto Matassa, Giuseppe Familiari, Sara Palchetti, Daniela Pozzi, Morteza Mahmoudi, Aldo Laganà Published in RSC advances, January 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Development of an image Mean Square Displacement (iMSD)-based method as a novel approach to study the intracellular trafficking of nanoparticles Luca Digiacomo, Michelle A. Digman, Enrico Gratton, Giulio Caracciolo Published in Acta biomaterialia, September 2016 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | The protein corona of circulating PEGylated liposomes Sara Palchetti, Valentina Colapicchioni, Luca Digiacomo, Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Giorgia La Barbera, Aldo Laganà Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, February 2016 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Stealth effect of biomolecular corona on nanoparticle uptake by immune cells Giulio Caracciolo, Sara Palchetti, Valentina Colapicchioni, Luca Digiacomo, Daniela Pozzi, Anna Laura Capriotti, Giorgia La Barbera, Aldo Laganà Published in Langmuir, October 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | The biomolecular corona of nanoparticles in circulating biological media Daniela Pozzi, Giulio Caracciolo, Luca Digiacomo, Valentina Colapicchioni, Sara Palchetti, Anna Laura Capriotti, Chiara Cavaliere, Riccardo Zenezini Chiozzi, Antonio Puglisi, Alado Laganà Published in Nanoscale, July 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Lipid composition: a ‘key factor’ for the rational manipulation of the liposome–protein corona by liposome design Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Heinz Amenitsch, Aldo Laganà Published in RSC advances, July 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Liposome–protein corona in a physiological environment: challenges and opportunities for targeted delivery of nanomedicines Giulio Caracciolo Published in Nanomedicine: Nanotechnology, Biology and Medicine, April 2015 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
| | Size and charge of nanoparticles following incubation with human plasma of healthy and pancreatic cancer patients Giulio Caracciolo, Damiano Caputo, Daniela Pozzi, Valentina Colapicchioni, Roberto Coppola Published in Colloids and Surfaces B: Biointerfaces, November 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: paper |
 | The liposome–protein corona in mice and humans and its implications for in vivo delivery Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Susy Piovesana, Giorgia La Barbera, Augusto Amici, Alado Laganà Published in Journal of Materials Chemistry B, September 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Effect of polyethyleneglycol (PEG) chain length on the bio-nano-interactions between PEGylated lipid nanoparticles and biological fluids: from nanostructure to uptake in cancer cells Daniela Pozzi, Valentina Colapicchioni, Giulio Caracciolo, Susy Piovesana, Anna Laura Capriotti, Sara Palchetti, Stefania De Grossi, Anna Riccioli, Heinz Amenitsch, Aldo Laganà Published in Nanoscale, March 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: interplay between nanostructure and composition Daniela Pozzi, Cristina Marchini, Francesco Cardarelli, Fabrizio Salomone, Stefano Coppola, Maura Montani, Maria Elexpuru Zabaleta, Michelle A. Digman, Enrico Gratton, Valentina Colapicchioni, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Selective targeting capability acquired with a protein corona adsorbed on the surface of 1, 2-dioleoyl-3-trimethylammonium propane/DNA nanoparticles Giulio Caracciolo, Francesco Cardarelli, Daniela Pozzi, Fabrizio Salomone, Giuseppe Maccari, Giuseppe Bardi, Anna Laura Capriotti, Chiara Cavaliere, Massimiliano Papi, Aldo Laganà Published in ACS applied materials & interfaces, December 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
 | Mechanistic understanding of gene delivery mediated by highly efficient multicomponent envelope-type nanoparticle systems Daniela Pozzi, Cristina Marchini, Francesco Cardarelli, Alessandro Rossetta, Valentina Colapicchioni, Augusto Amici, Maura Montani, Stefania Motta, Paola Brocca, Laura Cantù, Giulio Caracciolo Published in Molecular pharmaceutics, December 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |
| | Time evolution of nanoparticle–protein corona in human plasma: relevance for targeted drug delivery Ana Lilia Barrán-Berdón, Daniela Pozzi, Giulio Caracciolo, Anna Laura Capriotti, Giuseppe Caruso, Chiara Cavaliere, Anna Riccioli, Sara Palchetti, Aldo Laganà Published in Langmuir, April 2013 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
 | Cationic liposome/DNA complexes: from structure to interactions with cellular membranes Giulio Caracciolo, Heinz Amenitsch Published in European biophysics journal, October 2012 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review |
| | Cholesterol-dependent macropinocytosis and endosomal escape control the transfection efficiency of lipoplexes in CHO living cells Francesco Cardarelli, Daniela Pozzi, Angelo Bifone, Cristina Marchini, Giulio Caracciolo Published in Molecular pharmaceutics, February 2012 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Evolution of the protein corona of lipid gene vectors as a function of plasma concentration Giulio Caracciolo, Daniela Pozzi, Anna Laura Capriotti, Chiara Cavaliere, Patrizia Foglia, Heinz Amenitsch, Aldo Lagana Published in Langmuir, December 2011 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
| | Surface adsorption of protein corona controls the cell internalization mechanism of DC-Chol–DOPE/DNA lipoplexes in serum Giulio Caracciolo, Luciano Callipo, Sofia Candeloro De Sanctis, Chiara Cavaliere, Daniela Pozzi, Aldo Laganà Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2010 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |