Morteza Mahmoudi

When we virtually met Morteza on a popular social media, we wouldn't have thought our partnership would become so close and fruitful. A few years later, a lobster salad in a pleasant Boston venue marked the beginning of an enduring scientific marriage. As a renowned nanoscientist in the field of bio-nano interactions and father of the “personalized protein corona”, we are so glad that Morteza shares his own research interests with the lab and actively participates in many common research projects about the protein corona. In addition to all this, Morteza is also the founder and director of the Academic Parity Movement, a nonprofit organization that aims to address academic bullying through research and awareness.

Some publications with our group

Protein corona profile of graphene oxide allows detection of glioblastoma multiforme using a simple one-dimensional gel electrophoresis technique: a proof-of-concept study Riccardo Di Santo, Erica Quagliarini, Luca Digiacomo, Daniela Pozzi, Angelina Di Carlo, Damiano Caputo, Andrea Cerrato, Carmela Maria Montone, Morteza Mahmoudi, Giulio Caracciolo Published in Biomaterials science, March 2021 (see publication) Research themes: Type: Paper

Optimal centrifugal isolating of liposome–protein complexes from human plasma Luca Digiacomo, Francesca Giulimondi, Anna Laura Capriotti, Susy Piovesana, Carmela Maria Montone, Riccardo Zenezini Chiozzi, Aldo Laganà, Morteza Mahmoudi, Daniela Pozzi, Giulio Caracciolo Published in Nanoscale Advances, March 2021 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper

A mechanistic explanation of the inhibitory role of the protein corona on liposomal gene expression Sara Palchetti, Luca Digiacomo, Francesca Giulimondi, Daniela Pozzi, Giovanna Peruzzi, Gianmarco Ferri, Heinz Amenitsch, Francesco Cardarelli, Morteza Mahmoudi, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2020 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Challenges in molecular diagnostic research in cancer nanotechnology Giulio Caracciolo, Hojatollah Vali, Anna Moore, Morteza Mahmoudi Published in Nano Today, August 2019 (see publication) Research themes: Nanomaterials for cancer detection Type: News and opinions

Interplay of protein corona and immune cells controls blood residency of liposomes Francesca Giulimondi, Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Elisabetta Vulpis, Anna Laura Capriotti, Riccardo Zenezini Chiozzi, Aldo Laganà, Heinz Amenitsch, Laura Masuelli, Giovanna Peruzzi, Morteza Mahmoudi, Isabella Screpanti, Alessandra Zingoni, Giulio Caracciolo Published in Nature communications, August 2019 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Disease-specific protein corona sensor arrays may have disease detection capacity Giulio Caracciolo, Reihaneh Safavi-Sohi, Reza Malekzadeh, Hossein Poustchi, Mahdi Vasighi, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Aldo Laganà, Mohammad Hajipour, Marina Di Domenico, Angelina Di Carlo, Damiano Caputo, Haniyeh Aghaverdi, Massimiliano Papi, Valentina Palmieri, Angela Santoni, Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Kenneth S Suslick, Morteza Mahmoudi Published in Nanoscale Horizons, June 2019 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper

Effect of molecular crowding on the biological identity of liposomes: an overlooked factor at the bio-nano interface Luca Digiacomo, Francesca Giulimondi, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale Advances, May 2019 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper

Exploitation of nanoparticle-protein interactions for early disease detection Massimiliano Papi, Valentina Palmieri, Sara Palchetti, Daniela Pozzi, Luca Digiacomo, Elia Guadagno, Marialaura del Basso De Caro, Marina Di Domenico, Serena Ricci, Roberto Pani, Morteza Mahmoudi, Angelina Di Carlo, Giulio Caracciolo Published in Applied Physics Letters, April 2019 (see publication) Research themes: Liposomes and lipid nanoparticles, Nanomaterials for cancer detection Type: Paper

Brain targeting by liposome–biomolecular corona boosts anticancer efficacy of temozolomide in glioblastoma cells Antonietta Arcella, Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Anna Laura Capriotti, Luigi Frati, Maria Antonietta Oliva, Georgia Tsaouli, Rossella Rota, Isabella Screpanti, Morteza Mahmoudi, Giulio Caracciolo Published in ACS Chemical Neuroscience, July 2018 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles Luca Digiacomo, Francesco Cardarelli, Daniela Pozzi, Sara Palchetti, Michelle A. Digman, Enrico Gratton, Anna Laura Capriotti, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale, October 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Biological identity of nanoparticles in vivo: clinical implications of the protein corona Giulio Caracciolo, Omid C. Farokhzad, Morteza Mahmoudi Published in Trends in Biotechnology, March 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Review

In vivo protein corona patterns of lipid nanoparticles Augusto Amici, Giulio Caracciolo, Luca Digiacomo, Valentina Gambini, Cristina Marchini, Martina Tilio, Anna Laura Capriotti, Valentina Colapicchioni, Roberto Matassa, Giuseppe Familiari, Sara Palchetti, Daniela Pozzi, Morteza Mahmoudi, Aldo Laganà Published in RSC advances, January 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper

Nanoparticles-cell association predicted by protein corona fingerprints Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Giovanna Peruzzi, Elisa Micarelli, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale, June 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper

Exploitation of nanoparticle–protein corona for emerging therapeutic and diagnostic applications Sara Palchetti, Daniela Pozzi, Morteza Mahmoudi, Giulio Caracciolo Published in Journal of Materials Chemistry B, May 2016 (see publication) Research themes: Nanomaterials for cancer detection Type: Review

Exploring cellular interactions of liposomes using protein corona fingerprints and physicochemical properties Arafeh Bigdeli, Sara Palchetti, Daniela Pozzi, Mohammad Reza Hormozi-Nezhad, Francesca Baldelli Bombelli, Giulio Caracciolo, Morteza Mahmoudi Published in ACS nano, March 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper