Enrico Gratton
Laboratory for Fluorescence Dynamics, University of California Irvive, USA
Enrico is the founder and principal investigator of the Laboratory for Fluorescence Dynamics and he is one of the most eminent scientists in the field of fluorescence spectroscopy worldwide. Enrico generously allowed us to join his lab for many months helping us to explore the mechanisms of nanovector-cell interaction with unprecedented level of accuracy. Fun evenings at Enrico's home in San Clemente with an amazing view of the Pacific Ocean are a memorable event.
Some publications with our group
An apolipoprotein-enriched biomolecular corona switches the cellular uptake mechanism and trafficking pathway of lipid nanoparticles Luca Digiacomo, Francesco Cardarelli, Daniela Pozzi, Sara Palchetti, Michelle A. Digman, Enrico Gratton, Anna Laura Capriotti, Morteza Mahmoudi, Giulio Caracciolo Published in Nanoscale, October 2017 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
Development of an image Mean Square Displacement (iMSD)-based method as a novel approach to study the intracellular trafficking of nanoparticles Luca Digiacomo, Michelle A. Digman, Enrico Gratton, Giulio Caracciolo Published in Acta biomaterialia, September 2016 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: Paper |
The intracellular trafficking mechanism of Lipofectamine-based transfection reagents and its implication for gene delivery Francesco Cardarelli, Luca Digiacomo, Cristina Marchini, Augusto Amici, Fabrizio Salomone, Giuseppe Fiume, Alessandro Rossetta, Enrico Gratton, Daniela Pozzi, Giulio Caracciolo Published in Scientific reports, May 2016 (see publication) Research themes: Liposomes and lipid nanoparticles Type: Paper |
Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: interplay between nanostructure and composition Daniela Pozzi, Cristina Marchini, Francesco Cardarelli, Fabrizio Salomone, Stefano Coppola, Maura Montani, Maria Elexpuru Zabaleta, Michelle A. Digman, Enrico Gratton, Valentina Colapicchioni, Giulio Caracciolo Published in Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2014 (see publication) Research themes: Nanocarriers for drug and gene delivery, Liposomes and lipid nanoparticles Type: paper |